Addison Disease
- Addison's Disease
- Primary Adrenal Insufficiency
- Primary Adrenocortical Insufficiency
- Primary Hypoadrenalism
- Addisons Disease
- Adrenal Insufficiency, Primary
Definition: An adrenal disease characterized by the progressive destruction of the ADRENAL CORTEX, resulting in insufficient production of ALDOSTERONE and HYDROCORTISONE. Clinical symptoms include ANOREXIA; NAUSEA; WEIGHT LOSS; MUSCLE WEAKNESS; and HYPERPIGMENTATION of the SKIN due to increase in circulating levels of ACTH precursor hormone which stimulates MELANOCYTES.
http://www.hon.ch/HONselect/RareDiseases/EN/C19.053.500.263.html
44http://www.hon.ch/HONselect/RareDiseases/EN/C19.053.500.263.html
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