Evista is an oral selective estrogen receptor modulator - royaldrugstore
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Evista used for reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and those at high risk for invasive breast cancer.
1 March 2014, Perth (http://royaldrugstore.co/) : Evista which contain Raloxifene medication is a selective estrogen receptor modulator (SERM) prescribed for treatment and prevention of osteoporosis in postmenopausal women. It is also used for reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and those at high risk for invasive breast cancer. It decreases bone turnover and increases bone density.
Mechanism of action
Estrogen is a hormone which among other actions, regulates the turnover (formation and destruction) of bone. Decreases in estrogen levels that are seen after menopause or after removal of the ovaries, lead to a loss of bone density and weakened bones, a condition called osteoporosis. Raloxifene decreases bone turnover and increases bone density although not to the same extent as estrogen itself. This makes bones stronger and prevents fractures in women with osteoporosis. Raloxifene is called a "selective estrogen receptor modulator" since it has effects like estrogen on some tissues but inhibits the effects of estrogen on other tissues. Raloxifene decreases low density lipoprotein (LDL or "bad") cholesterol in the blood; however, unlike estrogen, raloxifene does not increase high density lipoprotein (HDL or "good") cholesterol. The FDA approved raloxifene in December 1997.
Contraindications
Contraindicated in patients with allergy to the drug; active or past history of venous blood clot events including deep vein thrombosis, pulmonary embolism and retinal vein thrombosis, pregnancy, nursing mothers.
Warnings and Precautions:
You should follow the diet and exercise recommended by the doctor regularly.
Calcium and Vitamin D should be taken if needed. Monitor your body weight regularly to prevent bone weakness. It may cause blood clots, so avoid sitting in one place. It is not recommended for men. Caution needed for pregnant women, elderly, and children, patients with history of heart failure, liver or kidney disease, excess in triglycerides in blood.
Side Effects:
Serious adverse effects- Deep vein thrombosis (clotting in the deep veins), pulmonary embolus, stroke. Most Common- Hot flushes, leg cramps, sweating, sleep disorders, peripheral edema, vaginal bleeding; flu-like symptoms, rashes, headache. Gastrointestinal- Nausea, vomiting, diarrhea, GI disturbances. Metabolic- Weight gain. Musculoskeletal- Joint pain, muscle pain, inflammation of joints, tendon disorder. Central Nervous System- Depression, sleeplessness, dizziness, nerve disease. Respiratory- Inflammation of respiratory tract, runny nose, increased cough. Skin- Rash, sweating. Eye- Inflammation of conjunctiva. Genitourinary- Urinary tract infection, inflammation of vagina, vaginal bleeding, uterine disorder. Potentially Fatal- Endometrial carcinoma and thromboembolic events. Storage Conditions:
Oral: Store at 15-30°C.Keep this medication in an airtight container, and room temperature. Keep away from children.
For more please visit :
James Keneally http://royaldrugstore.co/ Perth, Western Australia, Australia JamesKeneally0122@gmail.com
Hi everyone, this is James Keneally from Australia . I am completed P.HD in pharmacy. I do lots of work in pharmacy but now I am working in royaldrugstore.co. I also write blog on all health related product like Zithromax,http://royaldrugstore.co/ProductDetails.aspx?pkid=13&catId=2, protonix, Zyban, proscar , Meloxicam, pristiq, etc.
Rate this! 1-5 starsMechanism of action
Estrogen is a hormone which among other actions, regulates the turnover (formation and destruction) of bone. Decreases in estrogen levels that are seen after menopause or after removal of the ovaries, lead to a loss of bone density and weakened bones, a condition called osteoporosis. Raloxifene decreases bone turnover and increases bone density although not to the same extent as estrogen itself. This makes bones stronger and prevents fractures in women with osteoporosis. Raloxifene is called a "selective estrogen receptor modulator" since it has effects like estrogen on some tissues but inhibits the effects of estrogen on other tissues. Raloxifene decreases low density lipoprotein (LDL or "bad") cholesterol in the blood; however, unlike estrogen, raloxifene does not increase high density lipoprotein (HDL or "good") cholesterol. The FDA approved raloxifene in December 1997.
Contraindications
Contraindicated in patients with allergy to the drug; active or past history of venous blood clot events including deep vein thrombosis, pulmonary embolism and retinal vein thrombosis, pregnancy, nursing mothers.
Warnings and Precautions:
You should follow the diet and exercise recommended by the doctor regularly.
Calcium and Vitamin D should be taken if needed. Monitor your body weight regularly to prevent bone weakness. It may cause blood clots, so avoid sitting in one place. It is not recommended for men. Caution needed for pregnant women, elderly, and children, patients with history of heart failure, liver or kidney disease, excess in triglycerides in blood.
Side Effects:
Serious adverse effects- Deep vein thrombosis (clotting in the deep veins), pulmonary embolus, stroke. Most Common- Hot flushes, leg cramps, sweating, sleep disorders, peripheral edema, vaginal bleeding; flu-like symptoms, rashes, headache. Gastrointestinal- Nausea, vomiting, diarrhea, GI disturbances. Metabolic- Weight gain. Musculoskeletal- Joint pain, muscle pain, inflammation of joints, tendon disorder. Central Nervous System- Depression, sleeplessness, dizziness, nerve disease. Respiratory- Inflammation of respiratory tract, runny nose, increased cough. Skin- Rash, sweating. Eye- Inflammation of conjunctiva. Genitourinary- Urinary tract infection, inflammation of vagina, vaginal bleeding, uterine disorder. Potentially Fatal- Endometrial carcinoma and thromboembolic events. Storage Conditions:
Oral: Store at 15-30°C.Keep this medication in an airtight container, and room temperature. Keep away from children.
For more please visit :
James Keneally http://royaldrugstore.co/ Perth, Western Australia, Australia JamesKeneally0122@gmail.com
Hi everyone, this is James Keneally from Australia . I am completed P.HD in pharmacy. I do lots of work in pharmacy but now I am working in royaldrugstore.co. I also write blog on all health related product like Zithromax,http://royaldrugstore.co/ProductDetails.aspx?pkid=13&catId=2, protonix, Zyban, proscar , Meloxicam, pristiq, etc.
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