Topiramate is a sulfamate-substituted monosaccharide - onlinepillmart
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Topiramate seems to be effective in some people with bipolar mood disorders that have not responded to lithium and other mood-stabilizers.
London, ( http://onlinepillmart.com/ ) : Topiramate (brand name Topamax) is an anticonvulsant ( anticonvulsant ) drug.
Advantages: Topiramate seems to be effective in some people with bipolar mood disorders that have not responded to lithium and other mood-stabilizers. Some people who have not been able to tolerate any antidepressant because of switches to mania or increased speed or intensity of cycling, or because of the development of mixed states, have been able to tolerate therapeutic doses of anti- depressants when taking topiramate. For most people, topiramate has tolerable side effects and it can be taken twice a day. The weight loss that accompanies topiramate therapy in some instances is useful for those individuals who have gained weight while taking other mood stabilizing drugs. In some studies 20-50% of people taking topiramate lost weight.
Drug interaction: Topiramate has many drug-drug interactions. Some of the most common are listed below:
As topiramate inhibits carbonic anhydrase, use with other inhibitors of carbonic anhydrase (e.g. acetazolamide) increases the risk of kidney stones.
Enzyme inducers (e.g. carbamazepine) can increase the elimination of topiramate, possibly necessitating dose escalations of topiramate.
This drug may increase the plasma-levels of phenytoin.
This product itself is a weak inhibitor of CYP2C19 and induces CYP3A4; a decrease in plasma levels of estrogens and digoxin has been noted during topiramate therapy. This can reduce the effectiveness of oral contraceptives (the pill); use of alternative birth control methods is recommended. Neither intrauterine devices (IUDs) nor Depo-Provera are affected by topiramate.
Alcohol may cause increased sedation or drowsiness, and increase the risk of having a seizure.
[b]Warnings: People taking this drug should be aware of the following risks:
Avoid activities requiring mental alertness and coordination until drug effects are realized.
It may impair heat regulation, especially in children. Use caution with activities leading to an increased core temperature, such as strenuous exercise, exposure to extreme heat, or dehydration.
This drug may cause visual field defects.
It may decrease effectiveness of estrogen-containing oral contraceptives.
Taking this product in the 1st trimester of pregnancy may increase risk of cleft lip/cleft palate in infant.
Topiramate should not be suddenly discontinued, as this may cause increased seizure activity.
Avoid evening primrose (seizure threshold decreased).
[b]Dosage: Topiramate is usually initially prescribed at an initial dose of 12.5 -25 mg once or twice a day and the total daily dose is increased by 12.5 - 25 mg every week. When prescribed in addition to other anticonvulsants being used as mood stabilizers, the final dose is often between 100 and 200 mg per day. Some patient with Bipolar Disorder does well on as little as a total daily dose of 50 mg/day. When used for the control of the symptoms of PTSD the average final dose is about 175 mg/day (with a range of 25 - 500 mg/day).
Storage: Store at room temperature. Protect from heat, light and moisture. Keep away from reach of children.
Richard MacLeod http://onlinepillmart.com/ richardmacleod0122@gmail.com London, London, UK
Hi friends, this is Richard MacLeod from UK. I am completed P.HD in Pharmacy. Now working in onlinepillmart.com as medical adviser. Also i write blog on Men's and women’s health also other health related disease; like keppra , Xenical,Lamotrigine, Mifeprex, order topamax online etc.
Rate this! 1-5 starsAdvantages: Topiramate seems to be effective in some people with bipolar mood disorders that have not responded to lithium and other mood-stabilizers. Some people who have not been able to tolerate any antidepressant because of switches to mania or increased speed or intensity of cycling, or because of the development of mixed states, have been able to tolerate therapeutic doses of anti- depressants when taking topiramate. For most people, topiramate has tolerable side effects and it can be taken twice a day. The weight loss that accompanies topiramate therapy in some instances is useful for those individuals who have gained weight while taking other mood stabilizing drugs. In some studies 20-50% of people taking topiramate lost weight.
Drug interaction: Topiramate has many drug-drug interactions. Some of the most common are listed below:
As topiramate inhibits carbonic anhydrase, use with other inhibitors of carbonic anhydrase (e.g. acetazolamide) increases the risk of kidney stones. Enzyme inducers (e.g. carbamazepine) can increase the elimination of topiramate, possibly necessitating dose escalations of topiramate. This drug may increase the plasma-levels of phenytoin. This product itself is a weak inhibitor of CYP2C19 and induces CYP3A4; a decrease in plasma levels of estrogens and digoxin has been noted during topiramate therapy. This can reduce the effectiveness of oral contraceptives (the pill); use of alternative birth control methods is recommended. Neither intrauterine devices (IUDs) nor Depo-Provera are affected by topiramate. Alcohol may cause increased sedation or drowsiness, and increase the risk of having a seizure.[b]Warnings: People taking this drug should be aware of the following risks:
Avoid activities requiring mental alertness and coordination until drug effects are realized. It may impair heat regulation, especially in children. Use caution with activities leading to an increased core temperature, such as strenuous exercise, exposure to extreme heat, or dehydration. This drug may cause visual field defects. It may decrease effectiveness of estrogen-containing oral contraceptives. Taking this product in the 1st trimester of pregnancy may increase risk of cleft lip/cleft palate in infant. Topiramate should not be suddenly discontinued, as this may cause increased seizure activity. Avoid evening primrose (seizure threshold decreased).[b]Dosage: Topiramate is usually initially prescribed at an initial dose of 12.5 -25 mg once or twice a day and the total daily dose is increased by 12.5 - 25 mg every week. When prescribed in addition to other anticonvulsants being used as mood stabilizers, the final dose is often between 100 and 200 mg per day. Some patient with Bipolar Disorder does well on as little as a total daily dose of 50 mg/day. When used for the control of the symptoms of PTSD the average final dose is about 175 mg/day (with a range of 25 - 500 mg/day).
Storage: Store at room temperature. Protect from heat, light and moisture. Keep away from reach of children.
Richard MacLeod http://onlinepillmart.com/ richardmacleod0122@gmail.com London, London, UK
Hi friends, this is Richard MacLeod from UK. I am completed P.HD in Pharmacy. Now working in onlinepillmart.com as medical adviser. Also i write blog on Men's and women’s health also other health related disease; like keppra , Xenical,Lamotrigine, Mifeprex, order topamax online etc.
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