Carafate, Sucralfate, aluminum, ulcers, upper gastrointestinal tract, onlinepillmart

12 June 2014, London, UK, (http://onlinepillmart.com/) : Carafate contain Sucralfate is a unique oral drug that is used for treating ulcers of the upper gastrointestinal tract. Chemically, it is a complex of the disaccharide sugar, sucrose, combined with sulfate and aluminum. It is minimally absorbed into the body, and its actions are entirely on the lining of the stomach and duodenum. Although its mechanism of action is not entirely understood, the following actions are thought to be important for its beneficial effects:

INDICATIONS AND USAGE:

Sucralfate tablets, USP are indicated in:

 Short-term treatment (up to 8 weeks) of active duodenal ulcer. While healing with sucralfate may occur during the first week or two, treatment should be continued for 4 to 8 weeks unless healing has been demonstrated by x-ray or endoscopic examination.
 Maintenance therapy for duodenal ulcer patients at reduced dosage after healing of acute ulcers.

DOSAGE AND ADMINISTRATION:

 Active Duodenal Ulcer: The recommended adult oral dosage for duodenal ulcer is 1 g four times per day on an empty stomach.
 Antacids may be prescribed as needed for relief of pain but should not be taken within one-half hour before or after sucralfate.
 While healing with sucralfate may occur during the first week or two, treatment should be continued for 4 to 8 weeks unless healing has been demonstrated by x-ray or endoscopic examination.
 Maintenance Therapy: The recommended adult oral dosage is 1 g twice a day.
 Elderly: In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.

ADVERSE REACTIONS:

Adverse reactions to sucralfate in clinical trials were minor and only rarely led to discontinuation of the drug. In studies involving over 2700 patients treated with sucralfate tablets, adverse effects were reported in 129 (4.7%).

Constipation was the most frequent complaint (2%). Other adverse effects reported in less than 0.5% of the patients are listed below by body system:

 Gastrointestinal: diarrhea, nausea, vomiting, gastric discomfort, indigestion, flatulence, dry mouth
 Dermatological: pruritus, rash
 Nervous System: dizziness, insomnia, sleepiness, vertigo
 Other: back pain, headache

Storage: Store at 20° - 25°C (68° - 77°F). Protect from heat, light and moisture. Keep away from reach of children.

Richard MacLeod Dilantin review online richardmacleod0122@gmail.com London, UK

Hi friends, this is Richard MacLeod from UK. I am completed P.HD in Pharmacy. Now working in onlinepillmart.com as medical adviser. Also i write blog on Men's and women’s health also other health related disease; like Fexofenadine, Xenical,Lamotrigine, Mifeprex, etc.