Poor sleep during pregnancy can lead to lower birth weights and interrupt the immune processes

July 20th, 2013 (http://www.kamagrarx.net/) - Poor sleep quality and quantity during pregnancy can disrupt normal immune processes and lead to lower birth weights and other complications. Women with depression also are more likely than non-depressed women to suffer from disturbed sleep and to experience immune system disruption and adverse pregnancy outcomes. The results highlight the importance of identifying sleep problems in early pregnancy, especially in women who experience depression, since sleep is a modifiable behavior.

The earlier that sleep problems are identified, the sooner the physicians can work with pregnant women to implement solutions. Sufficient and high-quality sleep, both in women who are pregnant and non-pregnant as well as men, is necessary for a healthy immune system. Pregnancy is often connected with changes in sleep patterns, including insomnia symptoms, shortened sleep, and poor sleep quality. These disturbances can exacerbate the body's inflammatory responses and cause an overproduction of cytokines, which behave as signal molecules that communicate among immune cells. This study is the first to investigate this relationship during pregnancy as opposed to postpartum.

While cytokines are important for numerous pregnancy-related processes, excess cytokines can attack and cause destruction of tissue and destroy healthy cells in pregnant women, thereby hindering the ability to ward off disease. For mothers who are expecting, excess cytokines can disrupt spinal arteries leading to depression, the cause of vascular disease, cause of pre-term birth.

The study is the first to evaluate all factors -- inflammatory cytokines, depression and insomnia -- and their possible combined effect on pregnant women

The findings reveal:

• Women with depression and poor sleep are at greatest risk for adverse birth-related outcomes. Cytokine levels is one of the biological pathway through which this is achieved, particularly with regard to preterm birth. • Any change in immunity, such as poor sleep and/or depression, could set the stage for increased risk for adverse outcomes.

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